 |
 |
|
|
Articles 
Elena L. Navas-Nacher, Laura Colangelo, Craig Beam, and Philip Greenland Major coronary disease risk factors, many of which are modifiable, are strong contributors to prediction of future risk, even in young men. These data may help in formulating appropriate strategies to identify young men at heightened risk for death from coronary heart disease in later adulthood.
Milton C. Weinstein, Sue J. Goldie, Elena Losina, Calvin J. Cohen, John D. Baxter, Hong Zhang, April D. Kimmel, and Kenneth A. Freedberg Genotypic antiretroviral resistance testing following antiretroviral failure is cost-effective. Primary resistance testing also seems to be reasonably cost-effective and will become more so as the prevalence of primary resistance increases.
Scott D. Solomon, Robert J. Glynn, Sally Greaves, Umed Ajani, Jean-Lucien Rouleau, Francis Menapace, J. Malcolm O. Arnold, Charles Hennekens, and Marc A. Pfeffer Significant myocardial stunning with subsequent improvement of ventricular function occurred in most study patients after Q-wave anterior myocardial infarction. A lower peak creatine kinase level, an estimate of the extent of necrosis, is independently predictive of recovery of function. Early functional assessment had limited ability to predict recovery of ventricular function.
Brief Communications
Frank Gress, Klaus Gottlieb, Stuart Sherman, and Glen Lehman Endoscopic ultrasonography–guided fine-needle aspiration biopsy may be valuable in the evaluation of a pancreatic mass when results on other biopsy methods are negative but pancreatic cancer is suspected.
Reviews
Brian F. Gage, Stephan D. Fihn, and Richard H. White This case-based review describes the risk and benefits of prescribing antithrombotic therapy for a hypothetical 80-year-old man who has atrial fibrillation and hypertension, and it offers practical advice on managing warfarin therapy.
Position Papers
Ralph Gonzales, John G. Bartlett, Richard E. Besser, Richelle J. Cooper, John M. Hickner, Jerome R. Hoffman, and Merle A. Sande The guidelines in this issue provide evidence-based recommendations for evaluation and treatment of adults with acute respiratory illnesses. This paper describes the background and specific aims of and methods used to develop these principles. The goal of the principles is to provide clinicians with practical strategies for limiting antibiotic use to the patients who are most likely to benefit from it.
Vincenza Snow, Christel Mottur-Pilson, Ralph Gonzales for the American College of Physicians–American Society of Internal Medicine* This guideline describes the evidence and makes specific recommendations on how clinicians can differentiate upper respiratory tract infection as bacterial or viral in origin and on when use of antibiotics in upper respiratory tract infection is beneficial.
Ralph Gonzales, John G. Bartlett, Richard E. Besser, John M. Hickner, Jerome R. Hoffman, and Merle A. Sande The goals of this paper are to provide evidence-based recommendations for when to apply the diagnosis of upper respiratory tract infection and when to consider antibiotic treatment of adults with an uncomplicated upper respiratory tract infection.
Vincenza Snow, Christel Mottur-Pilson, John M. Hickner for the American College of Physicians–American Society of Internal Medicine* This guideline presents supporting evidence and makes specific recommendations on how clinicians evaluating acute sinusitis can differentiate bacterial causes from viral and how they can determine when antibiotic use is beneficial.
John M. Hickner, John G. Bartlett, Richard E. Besser, Ralph Gonzales, Jerome R. Hoffman, and Merle A. Sande This paper argues for a conservative approach to use of antibiotics in patients with sinusitis-like symptoms, consistent with efforts to reduce antibiotic use for respiratory infections in ambulatory patients.
Vincenza Snow, Christel Mottur-Pilson, Richelle J. Cooper, Jerome R. Hoffman for the American College of Physicians–American Society of Internal Medicine* This guideline presents evidence and makes specific recommendations on how clinicians can distinguish and diagnose pharyngitis caused by group A ß-hemolytic streptococcus. It also discusses when antibiotic use is beneficial and which antibiotics should be used.
Richelle J. Cooper, Jerome R. Hoffman, John G. Bartlett, Richard E. Besser, Ralph Gonzales, John M. Hickner, and Merle A. Sande Most immunocompetent adults with sore throat have acute infectious pharyngitis. Widespread antibiotic use in such patients has been based on an effort to treat bacterial (particularly streptococcal) pharyngitis. This paper addresses the rational treatment of nongonococcal, nondiphtherial acute pharyngitis in healthy adults.
Vincenza Snow, Christel Mottur-Pilson, Ralph Gonzales for the American College of Physicians–American Society of Internal Medicine* This guideline describes evidence and makes specific recommendations on how clinicians can differentiate between bacterial and viral causes of acute bronchitis and on when the use of antibiotics in acute bronchitis is beneficial.
Ralph Gonzales, John G. Bartlett, Richard E. Besser, Richelle J. Cooper, John M. Hickner, Jerome R. Hoffman, and Merle A. Sande Most cases of acute bronchitis occur in otherwise healthy adults, in whom this acute cough illness can be called "uncomplicated acute bronchitis." This paper discusses use of antibiotics in these patients.
Editorials
Michael S. Saag In this issue, Weinstein and colleagues provide evidence demonstrating the cost–benefit of resistance testing in patients with HIV infection. However, further virologic, clinical, and quality-adjusted life-year data should be obtained before therapeutic drug monitoring is implemented in routine practice.
On Being a Doctor
Paul Teplis A physician reflects on his experience as a medical student at a hospital medical clinic in 1946.
Letters Distant Healing
The Alcohol Hangover
Self-Study from Web-Based and Printed Guideline Material
Hypothyroidism in Two Patients after Hepatic Arterial Chemoembolization
Julie Low
Matthew K. Wynia
Aaron Levin
Phillip J. Cozzi
| ||||||||||||||||||||||||||||||||||||||||||||||||||||||
In this Issue
Articles
Previous Issue