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box In this Issue
  arrow Articles
  arrow Brief Communications
  arrow Reviews
  arrow Position Papers
  arrow Editorials
  arrow On Being a Doctor
  arrow Letters
  arrow Medical Writings: Book Notes
  arrow Current Clinical Issues
  arrow Ad Libitum
  arrow Ancillary Content
  arrow Summaries for Patients
  arrow PDF of Contents
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TABLE OF CONTENTS

20 March 2001 Volume 134 Issue 6
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Articles Back

Elena L. Navas-Nacher, Laura Colangelo, Craig Beam, and Philip Greenland

Major coronary disease risk factors, many of which are modifiable, are strong contributors to prediction of future risk, even in young men. These data may help in formulating appropriate strategies to identify young men at heightened risk for death from coronary heart disease in later adulthood.

Abstract | Full Text | PDF | Summary for Patients

Milton C. Weinstein, Sue J. Goldie, Elena Losina, Calvin J. Cohen, John D. Baxter, Hong Zhang, April D. Kimmel, and Kenneth A. Freedberg

Genotypic antiretroviral resistance testing following antiretroviral failure is cost-effective. Primary resistance testing also seems to be reasonably cost-effective and will become more so as the prevalence of primary resistance increases.

Abstract | Full Text | PDF | Summary for Patients

Scott D. Solomon, Robert J. Glynn, Sally Greaves, Umed Ajani, Jean-Lucien Rouleau, Francis Menapace, J. Malcolm O. Arnold, Charles Hennekens, and Marc A. Pfeffer

Significant myocardial stunning with subsequent improvement of ventricular function occurred in most study patients after Q-wave anterior myocardial infarction. A lower peak creatine kinase level, an estimate of the extent of necrosis, is independently predictive of recovery of function. Early functional assessment had limited ability to predict recovery of ventricular function.

Abstract | Full Text | PDF | Summary for Patients


Brief Communications Back

Frank Gress, Klaus Gottlieb, Stuart Sherman, and Glen Lehman

Endoscopic ultrasonography–guided fine-needle aspiration biopsy may be valuable in the evaluation of a pancreatic mass when results on other biopsy methods are negative but pancreatic cancer is suspected.

Abstract | Full Text | PDF | Summary for Patients


Reviews Back

Brian F. Gage, Stephan D. Fihn, and Richard H. White

This case-based review describes the risk and benefits of prescribing antithrombotic therapy for a hypothetical 80-year-old man who has atrial fibrillation and hypertension, and it offers practical advice on managing warfarin therapy.

Abstract | Full Text | PDF


Position Papers Back

Ralph Gonzales, John G. Bartlett, Richard E. Besser, Richelle J. Cooper, John M. Hickner, Jerome R. Hoffman, and Merle A. Sande

The guidelines in this issue provide evidence-based recommendations for evaluation and treatment of adults with acute respiratory illnesses. This paper describes the background and specific aims of and methods used to develop these principles. The goal of the principles is to provide clinicians with practical strategies for limiting antibiotic use to the patients who are most likely to benefit from it.

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Vincenza Snow, Christel Mottur-Pilson, Ralph Gonzales for the American College of Physicians–American Society of Internal Medicine*

This guideline describes the evidence and makes specific recommendations on how clinicians can differentiate upper respiratory tract infection as bacterial or viral in origin and on when use of antibiotics in upper respiratory tract infection is beneficial.

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Ralph Gonzales, John G. Bartlett, Richard E. Besser, John M. Hickner, Jerome R. Hoffman, and Merle A. Sande

The goals of this paper are to provide evidence-based recommendations for when to apply the diagnosis of upper respiratory tract infection and when to consider antibiotic treatment of adults with an uncomplicated upper respiratory tract infection.

Abstract | Full Text | PDF

Vincenza Snow, Christel Mottur-Pilson, John M. Hickner for the American College of Physicians–American Society of Internal Medicine*

This guideline presents supporting evidence and makes specific recommendations on how clinicians evaluating acute sinusitis can differentiate bacterial causes from viral and how they can determine when antibiotic use is beneficial.

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John M. Hickner, John G. Bartlett, Richard E. Besser, Ralph Gonzales, Jerome R. Hoffman, and Merle A. Sande

This paper argues for a conservative approach to use of antibiotics in patients with sinusitis-like symptoms, consistent with efforts to reduce antibiotic use for respiratory infections in ambulatory patients.

Abstract | Full Text | PDF

Vincenza Snow, Christel Mottur-Pilson, Richelle J. Cooper, Jerome R. Hoffman for the American College of Physicians–American Society of Internal Medicine*

This guideline presents evidence and makes specific recommendations on how clinicians can distinguish and diagnose pharyngitis caused by group A ß-hemolytic streptococcus. It also discusses when antibiotic use is beneficial and which antibiotics should be used.

Full Text | PDF

Richelle J. Cooper, Jerome R. Hoffman, John G. Bartlett, Richard E. Besser, Ralph Gonzales, John M. Hickner, and Merle A. Sande

Most immunocompetent adults with sore throat have acute infectious pharyngitis. Widespread antibiotic use in such patients has been based on an effort to treat bacterial (particularly streptococcal) pharyngitis. This paper addresses the rational treatment of nongonococcal, nondiphtherial acute pharyngitis in healthy adults.

Abstract | Full Text | PDF

Vincenza Snow, Christel Mottur-Pilson, Ralph Gonzales for the American College of Physicians–American Society of Internal Medicine*

This guideline describes evidence and makes specific recommendations on how clinicians can differentiate between bacterial and viral causes of acute bronchitis and on when the use of antibiotics in acute bronchitis is beneficial.

Full Text | PDF

Ralph Gonzales, John G. Bartlett, Richard E. Besser, Richelle J. Cooper, John M. Hickner, Jerome R. Hoffman, and Merle A. Sande

Most cases of acute bronchitis occur in otherwise healthy adults, in whom this acute cough illness can be called "uncomplicated acute bronchitis." This paper discusses use of antibiotics in these patients.

Abstract | Full Text | PDF


Editorials Back

Michael S. Saag

In this issue, Weinstein and colleagues provide evidence demonstrating the cost–benefit of resistance testing in patients with HIV infection. However, further virologic, clinical, and quality-adjusted life-year data should be obtained before therapeutic drug monitoring is implemented in routine practice.

Full Text | PDF


On Being a Doctor Back

Paul Teplis

A physician reflects on his experience as a medical student at a hospital medical clinic in 1946.

Full Text | PDF


Letters Back

Distant Healing

    John Astin, Elaine Harkness, and Edzard Ernst—RESPONSE

    Full Text | PDF

The Alcohol Hangover

    Jeffrey Wiese and Michael Shlipak—RESPONSE

    Full Text | PDF

Self-Study from Web-Based and Printed Guideline Material

    Douglas S. Bell, Gregg C. Fonarow, and Carol M. Mangione—RESPONSE

    Full Text | PDF

Hypothyroidism in Two Patients after Hepatic Arterial Chemoembolization

    Nicholas A. Tritos, Keith Stuart, and Pamela I. Hartzband

    Full Text | PDF


Medical Writings: Book Notes Back

Julie Low

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Matthew K. Wynia

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Current Clinical Issues  Back

Aaron Levin

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Ad Libitum Back

Phillip J. Cozzi

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Ancillary Content Back

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Summaries for Patients Back

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