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Articles 
Ferran Barbé, Lola R. Mayoralas, Joaquin Duran, Juan F. Masa, Andreu Maimó, Josep M. Montserrat, Carmen Monasterio, Margalida Bosch, Antoni Ladaria, Manuela Rubio, Ramon Rubio, Magdalena Medinas, Lourdes Hernandez, Silvia Vidal, Neil J. Douglas, and Alvar G.N. Agustí In patients with an apnea–hypopnea index of 30 or greater and no subjective daytime sleepiness, continuous positive airway pressure did not modify quality of life, objective sleepiness, vigilance, attention, memory, information processing, visuomotor coordination, or arterial blood pressure.
Mary A.M. Rogers, David Small, Debra A. Buchan, Carl A. Butch, Christine M. Stewart, Barbara E. Krenzer, and Harold L. Husovsky Use of a telecommunication service that consisted of automatic transmission of blood pressure data over telephone lines and weekly electronic transmission of reports to physicians reduced the mean arterial pressure of patients with established essential hypertension.
Jeremy B. Levy, A. Neil Turner, Andrew J. Rees, and Charles D. Pusey Patients with the Goodpasture syndrome (anti–glomerular basement membrane antibody disease with pulmonary hemorrhage) and severe renal failure should be considered for urgent immunosuppressive therapy, including plasma exchange, to maximize the chance of renal recovery. Patients in need of immediate dialysis are less likely to recover.
Brief Communications
Michael G. Shlipak, Darryl A. Elmouchi, David M. Herrington, Feng Lin, Deborah Grady, Mark A. Hlatky for the Heart and Estrogen/progestin Replacement Study Research Group In this study, the incidence of unrecognized myocardial infarction in women with known coronary disease was much lower than that noted in previous studies of populations without established coronary heart disease.
Reviews
Philip S. Mehler In addition to diagnosing anorexia nervosa and treating the multiple medical complications associated with this disorder, the primary care physician plays a central role in maintaining continuity of care throughout a variety of treatment settings.
Perspectives
John E. Calfee Pharmaceutical price controls offer short-term gains for a small proportion of patients at the cost of curtailing research that promises to bring far better therapies in the future. The notion that controls could provide reasonable incentives for future research has no foundation.
Editorials
Allan I. Pack and Greg Maislin Barbé and colleagues' findings on the efficacy of continuous positive airway pressure in patients with sleep apnea but no daytime sleepiness, reported in this issue, raise three important issues. First, why are some patients with high levels of respiratory disturbance during sleep not excessively sleepy? Second, what are the reasons for treating patients with obstructive sleep apnea? And finally, how can we identify patients with obstructive sleep apnea who will benefit from treatment?
Frank Davidoff It can hardly be a mystery why the price of prescription drugs in the United States has become such a contentious issue. What does the evidence tell us about the actual cost-effectiveness of prescription drugs and the need for the current outlays for drug development?
Eric B. Larson The 3 July 2001 issue of Annals will witness a changing of the guard. Frank Davidoff will exit gracefully after six and a half years as the highly capable, widely respected editor, passing the torch to a new editor, Harold Sox.
On Being a Doctor
Claude Matuchansky Jacques Rethel was a country doctor in a village located in the Manche area of Normandy. This wasn't the first time he'd been requisitioned by the Germans at a moment's notice to attend to their soldiers—usually high-ranking officers.
Letters Cyclooxygenase-2 Inhibition and Renal Function
Frederic W. Platt, David L. Gaspar, John L. Coulehan, Lucy Fox, Andrew J. Adler, W. Wayne Weston, Robert C. Smith, and Moira Stewart To center the medical interview on the patient as well as the disease, the physician must offer both nonverbal and verbal evidence that what the patient has to say is important. In the end, the two most useful physician qualities may be curiosity and patience—curiosity to ask questions such as "Tell me about yourself," and patience to wait for the answer.
Robert J.T. Joy
Kenneth W. Presberg
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