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Articles 
Jesper Lagergren, Reinhold Bergström, Hans-Olov Adami, and Olof Nyrén The use of lower esophageal sphincter–relaxing medications was associated with increased risk for esophageal adenocarcinoma.
Tom Forsén, Johan Eriksson, Jaakko Tuomilehto, Antti Reunanen, Clive Osmond, and David Barker The study findings are consistent with the hypothesis that type 2 diabetes is programmed in utero in association with low rates of fetal growth. The increased risk for type 2 diabetes related to small size at birth is further increased by high growth rates after 7 years of age.
Noriyuki Nakanishi, Koji Nakamura, Yoshio Matsuo, Kenji Suzuki, and Kozo Tatara The number of cigarettes smoked daily and the number of pack-years of exposure seemed to be associated with development of impaired fasting glucose and type 2 diabetes in middle-aged Japanese men.
Brief Communications
Kirk D. Miller, Miriam Cameron, Lauren V. Wood, Marinos C. Dalakas, and Joseph A. Kovacs Four patients receiving stavudine developed hepatic steatosis, lactic acidosis, and myopathy. Because hepatic steatosis may be life-threatening, physicians should consider it as a possible cause of elevated hepatic aminotransferase levels among patients taking stavudine.
Paul J. Jenkins, S. Aslam Sohaib, Scott Akker, Rachel R. Phillips, Kate Spillane, John A.H. Wass, John P. Monson, Ashley B. Grossman, G. Michael Besser, and Rodney H. Reznek The predominant pathology of median neuropathy in acromegaly seems to be increased edema of the median nerve within the carpal tunnel rather than extrinsic compression from increased volume of the carpal tunnel contents.
Academia and Clinic
Stephen I. Wasserman, Harry R. Kimball, F. Daniel Duffy for the Task Force on Recertification* In 2000, the American Board of Internal Medicine introduced a second-generation recertification process that builds on the current knowledge-centered program by adding assessments of clinical and communication skills, clinical performance, and medical outcomes.
Perspectives
Scott Burris, Peter Lurie, Daniel Abrahamson, and Josiah D. Rich Physicians and pharmacists can play an important role in providing syringe access by prescribing and dispensing syringes to patients who use injection drugs and cannot or will not enter drug treatment.
Editorials
Glenn M. Eisen In this issue, Lagergren and colleagues report that long-term use of drugs that promote lower esophageal sphincter relaxation may be responsible for about 10% of esophageal carcinomas. Although this study sheds light on a potential risk factor for esophageal carcinoma, further sound epidemiologic work is necessary.
Frank Davidoff Three recent changes to the Uniform Requirements for Manuscripts Submitted to Biomedical Journals deserve special mention: use of the concepts of race and ethnicity, authorship issues, and use of reporting guidelines for specific study designs.
On Being a Patient
Muhammad Asim Khan A physician reflects on his experience as a patient with complex, crippling illness for the past 44 years.
Letters Chronic Dizziness in Older Adults
Sister (Mary) Joseph's Nodule
Correction: Liver Injury and Rosiglitazone
Iain Chalmers and Ulrich Tröhler Conscientious physicians wishing to keep up to date with relevant information face a truly daunting task. Efforts to respond to this need are not new. More than two centuries ago, the first English-language journal of abstracts of books relevant to busy clinicians was published.
Mark J. DiNubile
David H. Spodick
Beatriz M. Rodriguez
Alicia Montañez
Keith Roach, Scott Stern, Diane Altkorn, Adam Cifu, and Wendy Levinson This Update covers articles on several topics relevant to general internal medicine, including osteoporosis, venous thromboembolism, cardiovascular protection, and influenza. | ||||||||||||||||||||||||||||||||||||||||||||||||||||
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