Table of Contents

December 1, 2009; 151 (11)

Articles

  • Some policymakers hypothesize that expanded insurance coverage before age 65 years might be associated with savings once people become eligible for Medicare. McWilliams and colleagues found that adjusted annual total Medicare spending was lower among 2951 continuously insured adults aged 64 to 74 years ($4773) than among 1616 adults who were uninsured before age 65 years ($5796). Previously uninsured adults also had higher adjusted annual hospitalization rates for complications related to cardiovascular disease or diabetes and for joint replacements.

  • Patients with end-stage idiopathic pulmonary fibrosis (IPF) are increasingly having bilateral rather than single-lung transplantation. In this study, after adjustment for baseline differences, survival did not differ between 2146 patients with IPF who had single-lung transplantation and 1181 patients who had bilateral lung transplantation, although causes of death differed. Single-lung transplantation conferred short-term survival benefit but long-term harm, whereas bilateral lung transplantation conferred short-term harm but long-term survival benefit.

  • National guidelines disagree on who should be screened for undiagnosed diabetes, and no existing diabetes risk score is highly generalizable or widely followed. Bang and coworkers developed a new screening score to allow people to self-assess their risk for diabetes. This score is easy to use and seems to perform better than existing methods. Studies are needed to evaluate it in diverse populations in real-world settings.

Academia and Clinic

  • Concerns have been raised about whether female researchers in academic medicine are as successful as men. Jagsi and associates found that although 31.4% of 1919 K08 awardees and 43.7% of 865 K23 awardees from 1997 to 2003 were female, women were less likely than men to receive an R01 award at 5 years (18.8% vs. 24.8%). Differences persisted at 10 years. Sex continued to be an independent significant predictor of R01 award attainment in multivariate analysis controlling for K award type, year of award, funding institute, institution, and specialty.

Perspectives

  • Recent data suggest that in adolescents and young adults, Fusobacterium necrophorum causes endemic pharyngitis at a rate similar to that of group A β-hemolytic streptococci. On the basis of published epidemiologic data, the author suggests that the diagnostic paradigm for adolescent pharyngitis be expanded to consider F. necrophorum. He proposes aggressive antibiotic treatment for F. necrophorum infection in adolescents and young adults who develop bacteremic symptoms and that physicians know the red flags for pharyngitis in this group.

Clinical Guidelines

  • The U.S. Preventive Services Task Force (USPSTF) recommends screening adults for depression when staff-assisted depression care supports are in place to assure accurate diagnosis, effective treatment, and follow-up (grade B recommendation). It recommends against routinely screening adults for depression when staff-assisted depression care supports are not in place. There may be considerations that support screening for depression in an individual patient (grade C recommendation).

  • To support the USPSTF recommendation statement in this issue, O'Connor and colleagues reviewed evidence on screening adults for depression in primary care, the benefits of depression treatment in older adults, and the harms of antidepressants. Primary care depression screening and care management programs with staff assistance can increase depression response and remission. No benefit was evident in screening programs without staff assistance in depression care. Antidepressant treatment does not seem to increase deaths from suicide. Risk for suicidal behavior was increased in young adults who received antidepressants, particularly paroxetine, but was reduced in older adults.

Editorials

  • In this issue, McWilliams and colleagues calculate that providing insurance to uninsured near-elderly adults would result in $98 billion of savings for Medicare in the first decade after they become eligible for Medicare. The editorialist asserts, however, that the data and methods used in this study do not support causal interpretations and that savings to Medicare are unlikely to be as large as suggested.

  • In this issue, Jagsi and associates report that men achieve R01 funding 25% to 30% more often than women. The editorialist discusses the social and cultural factors that may be contributing to this “leaky pipeline.”

On Being a Doctor

Letters

Medical Writings: Book Notes

Ad Libitum

Medical Notices

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In the Clinic