Mortality in Patients with Implanted Automatic Defibrillators

  1. M. MIROWSKI, M.D.;
  2. PHILIP R. REID, M.D.;
  3. ROGER A. WINKLE, M.D.;
  4. MORTON M. MOWER, M.D.;
  5. LEVI WATKINS, Jr., M.D.;
  6. EDWARD B. STINSON, M.D.;
  7. LAWRENCE S. C. GRIFFITH, M.D.;
  8. CLAYTON H. KALLMAN, SC.M.; and
  9. MYRON L. WEISFELDT, M.D.
  1. Baltimore, Maryland; and Stanford, California

    Abstract

    Fifty-two patients who survived several arrhythmic cardiac arrests had implantation of an automatic defibrillator along with additional cardiovascular surgery as indicated. The mean follow-up was 14.4 months and the longest was 3 years. In the hospital, the implanted devices identified and reverted 82 episodes of spontaneous and 81 of 99 episodes of induced malignant tachyarrhythmias. There were 62 automatic resuscitations in 17 patients outside the hospital. Twelve patients died; four of the deaths were not witnessed. These deaths represent a 22.9% total and 8.5% sudden-death 1-year mortality rate. Because the expected 1-year mortality in patients without the automatic defibrillator was calculated to be 48%, there was an estimated 52% decrease in anticipated total deaths. The automatic implantable defibrillator can identify and correct potentially lethal ventricular tachyarrhythmias, leading to a substantial increase in 1-year survival in properly selected high-risk patients.

    Article and Author Information

    • ▸From the Department of Medicine, Sinai Hospital of Baltimore, the Departments of Medicine and Surgery, The Johns Hopkins Medical Institutions, Baltimore, Maryland; and the Division of Cardiology and the Department of Cardiovascular Surgery, Stanford University Medical Center, Stanford, California.

    • ▸Requests for reprints should be addressed to M. Mirowski, M.D.; Department of Medicine, Sinai Hospital of Baltimore; Baltimore, MD 21215.

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