Hyperparathyroidism in Twins

  1. ALLAN PONT, M.D.;
  2. MAURICE FOX, M.D.;
  3. RONALD C. MERRELL, M.D.;
  4. ERIC GOLDMAN, M.D.;
  5. HEWLETT LEE, M.D.; and
  6. DAVID D. OAKES, M.D.
  1. Santa Clara Valley Medical Center,
    San Jose, California
    ; Palo Alto Medical Clinic,
    Palo Alto, California
    ; and Stanford University,
    Stanford, California

    Excerpt

    In 1936 Goldman and Smyth (1) reported the first cases of hyperparathyroidism in siblings. It is now generally accepted that familial hyperparathyroidism can occur both with (2) and without (3) other components of the multiple endocrine neoplasia syndromes. In 1958, Snapper and colleagues (4) documented the only previous example of hyperparathyroidism in twins. We recently encountered identical twins with hyperparathyroidism. One of the brothers became hypoparathyroid after surgery for a parathyroid adenoma. When his twin brother's parathyroid adenoma was removed, fragments of it were transplanted into the hypoparathyroid patient's right forearm restoring him to normocalcemia.

    In December 1980 a 22-year-old

    Article and Author Information

    • ▸Requests for reprints should be addressed to Allan Pont, M.D.; Children's Hospital of San Francisco, 3905 Sacramento Street #101; San Francisco, CA 94118.

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