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Peptide Radioimmunoassays in Clinical Medicine
- MICHAEL C. GEOKAS, M.D., Ph.D.;
- ROSALYN S. YALOW, Ph.D.;
- EUGENE W. STRAUS, M.D.; and
- ERNEST M. GOLD, M.D.
Abstract
The radioimmunoassay technique, first developed for the determination of hormones, has been applied to many substances of biologic interest by clinical and research laboratories around the world. It has had an enormous effect in medicine and biology as a diagnostic tool, a guide to therapy, and a probe for the fine structure of biologic systems. For instance, the assays of insulin, gastrin, secretin, prolactin, and certain tissue-specific enzymes have been invaluable in patient care. Further refinements of current methods, as well as the emergence of new immunoassay techniques, are expected to enhance precision, specificity, reliability, and convenience of the radioimmunoassay in both clinical and research laboratories.
Article and Author Information
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▸An edited transcription of an Interdepartmental Dean's Conference arranged by the Departments of Medicine of the University of California, Davis, School of Medicine, Davis, California; and the Veterans Administration Medical Center, Martinez, California.
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▸Authors who wish to cite a section of this conference and specifically indicate its author can use this example for the form of the reference:
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YALOW RS. Roles for a species-specific insulin antibody, pp. 389-91. In: GEOKAS MC, moderator. Peptide radioimmunoassays in clinical medicine. Ann Intern Med. 1982;97:389-407.
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▸Requests for reprints should be addressed to Michael C. Geokas, M.D., Ph.D.; Chief, Medical Service, Department of Medicine, Veterans Administration Medical Center; 150 Muir Road; Martinez, CA 94553.
- ©1982 American College of Physicians
