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Penicillin-Resistant Gonococcal Arthritis
A Report of Four Cases
- RENEE Z. RINALDI, M.D.;
- WILLIAM O. HARRISON, M.D.; and
- PENG THIM FAN, M.D.
Abstract
Complicated and disseminated gonococcal infections caused by penicillinase-producing Neisseria gonorrhoeae are beginning to be reported. We describe four patients with gonococcal septic arthritis in whom penicillinaseproducing gonococci were isolated from joint fluid. These cases responded to antibiotic therapy that was known to be effective against penicillinase-producing N. gonorrhoeae.
Article and Author Information
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▸ From the Rheumatology Section, Wadsworth Medical Center. Los Angeles. California: and the Clinical Investigation Center. Naval Regional Medical Center. San Diego, California.
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Grant support: supported in part by the Bureau of Medicine and Surgery, Clinical Investigation Program, Protocol #8-16-1140, and Wadsworth Medical Research.
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The opinions or assertions expressed in this paper are those of the authors and are not to be construed as official or as necessarily reflecting the views of the Veterans Administration, the Department of the Navy, or the naval service at large.
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▸ Requests for reprints should be addressed to Capt. William O. Harrison, MC, USN; Clinical Investigation Center, Naval Regional Medical Center; San Diego, CA 92134.
