Estrogen Receptor Activity in a Case of Hodgkin's Disease

Excerpt

The discovery by Jensen and colleagues (1) and others (2) of the presence of estrogen receptors in human breast cancers and the subsequent correlation of the presence of hormone receptors and response to therapy have had profound effects on the modern management of patients with advanced cancer of the breast. Estrogen receptor activity has also been identified in normal liver, endometrium, and pancreas; in neoplasms other than those of breast, including adenocarcinoma of endometrium, colon, and ovary; and in malignant melanoma (3). To date these observations have been of only modest therapeutic significance. Presented here is the case of a