RSS Feeds
Granulomatous Hepatitis Secondary to Carbamazepine
- MICHAEL LEVY, M. D.;
- MICHAEL W. GOODMAN, M.D.;
- BRUCE J. VAN DYNE, M.D.; and
- HATTON W. SUMNER, M.D.
Abstract
Three cases of carbamazepine-induced granulomatous hepatitis are reported. Each patient had ingested carbamazepine for less than 1 month before presenting with a febrile illness suggestive of biliary tract infection. After withdrawal of carbamazepine, symptoms disappeared rapidly. Histologically, all patients had granulomatous hepatitis. Two patients also had acute cholangitis. Carbamazepine-induced liver injury can be confused clinically and pathologically with biliary tract infection.
Article and Author Information
-
▸From the Department of Medicine, Hennepin County Medical Center, Department of Pathology, Veterans Administration Medical Center, and the University of Minnesota; Minneapolis, Minnesota.
-
▸Requests for reprints should be addressed to Michael W. Goodman, M.D.; Department of Medicine, Hennepin County Medical Center, 701 Park Avenue South; Minneapolis, MN 55415.
