Does Triggered Activity Have a Role in the Genesis of Cardiac Arrhythmias?

  1. MICHAEL R. ROSEN, M.D.; and
  2. ROBERT F. REDER, M.D.
  1. New York, New York

    Abstract

    Whether triggered activity plays a role in the genesis of cardiac arrhythmias is considered in this review. The characteristics of triggered activity are compared with those of automaticity and re-entry at the cellular electrophysiologic level, and these observations then are related to cardiac arrhythmias. We stress, however, that the relation between triggered activity and clinical arrhythmias still is largely speculative and that further experimental and clinical study is needed before the presence (or absence) of a role for triggered activity is verified.

    Article and Author Information

    • ▸From the Departments of Pharmacology and Pediatrics, Columbia University College of Physicians and Surgeons; New York, New York.

    • Grant support: in part by grants HL-12738 and LH-07419 from the National Heart, Lung, and Blood Institute and grants from the New York Heart Association.

    • ▸Requests for reprints should be addressed to Michael R. Rosen, M.D.; Department of Pharmacology, College of Physicians and Surgeons, 630 West 168th Street; New York, NY 10032.

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    1. Ann Intern Med June 1, 1981 vol. 94 no. 6 794-801
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