Kawasaki Disease in a Healthy Young Adult

  1. HENRY MILGROM, M.D.;
  2. ERSKINE L. PALMER, Ph.D.;
  3. SUSAN F. SLOVIN, Ph.D.;
  4. DAVID M. MORENS, M.D.;
  5. STANLEY D. FREEDMAN, M.D.; and
  6. JOHN H. VAUGHAN, M.D.
  1. La Jolla, California, and Atlanta, Georgia

    Abstract

    This report describes a 26-year-old woman who fulfills the criteria for the diagnosis of Kawasaki disease or mucocutaneous lymph node syndrome, an acute febrile illness that usually afflicts young children. The diagnosis is made in persons with fever lasting 5 or more days when four of the following criteria are met: bilateral injection of ocular conjunctivae; involvement of the mucous membranes of the upper respiratory tract consisting of any combination of the following—redness and fissuring of lips; "strawberry tongue," or erythema of the pharynx; involvement of the peripheral extremities characterized in the early stages by an indurative erythematous rash of palms and soles followed by membranous desquamation; polymorphous nonvesicular truncal exanthem; and acute nonsuppurative enlargement of cervical lymph nodes. An added stipulation is that the illness must not be attributable to a known disease process.

    Article and Author Information

    • ▸From the Department of Clinical Research, Scripps Clinic and Research Foundation, La Jolla, California; and the Virology Division, Bureau of Laboratories, Center for Disease Control, Atlanta, Georgia.

    • Grant support: grants AI 10386, AM 07144, and AM 21175, National Institutes of Health.

    • ▸Requests for reprints should be addressed to Susan F. Slovin, Ph.D.; Department of Clinical Research, Scripps Clinic and Research Foundation, 10666 North Torrey Pines Road; La Jolla, CA 92037.

      • Received July 10, 1979.
      • Accepted January 11, 1980.
    « Previous | Next Article »Table of Contents