RSS Feeds
Sjögren's Syndrome (Sicca Syndrome): Current Issues
- HARALAMPOS M. MOUTSOPOULOS, M.D.;
- THOMAS M. CHUSED, M.D.;
- DEAN L. MANN, M.D.;
- JOHN H. KLIPPEL, M.D.;
- ANTHONY S. FAUCI, M.D.;
- MICHAEL M. FRANK, M.D.;
- THOMAS J. LAWLEY, M.D.; and
- MAX I. HAMBURGER, M.D.
Abstract
This paper outlines the clinical, serologic, and immunogenetic differences and similarities of Sjögren's syndrome alone (primary) and Sjögren's syndrome associated with rheumatoid arthritis and systemic lupus erythematosus (secondary). The immunoregulation in Sjögren's syndrome is discussed and the incidence of immune complex-like material, its nature, pathophysiology, and clearance by the Fc receptor of the reticuloendothelial system presented.
Article and Author Information
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▸An edited transcription of a Combined Clinical Staff Conference at the Clinical Center, Bethesda, Maryland, 19 April 1979, by the National Institute of Dental Research, National Institutes of Health, U.S. Department of Health, Education, and Welfare.
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▸Authors who wish to cite a section of this conference and specifically indicate its author can use this example for the form of reference:
CHUSED TM. Lymphoma and autoantibodies in Sjögren's syndrome, pp. 213-6. In: MOUTSOPOULOS HM, moderator. Sjögren's syndrome (sicca syndrome): current issues. Ann Intern Med. 1980;92(Part 1):212-26.
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Dr. Moutsopoulos is currently Professor of Medicine at the School of Medicine, University of Ioannina, Ioannina, Greece.
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öRequests for reprints should be addressed to Haralampos M. Moutsopoulos, M.D.; Room 2B10, Building 10, National Institutes of Health; Bethesda, MD 20205.
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- Received November 8, 1979.
- Accepted November 29, 1979.
