Renovascular Hypertension: Treatment by Percutaneous Transluminal Dilatation

  1. U. KUHLMANN, M.D.;
  2. W. VETTER, M.D.;
  3. J. FURRER, M.D.;
  4. U. LÜTOLF, M.D.;
  5. W. SIEGENTHALER, M.D.; and
  6. A. GRÜNTZIG, M.D.
  1. Zurich,
    Switzerland

    Abstract

    Eight patients with unilateral renovascular hypertension underwent percutaneous transluminal dilatation. In seven, renal-artery stenoses were caused by atherosclerotic lesions and in one, by fibromuscular hyperplasia. After a 6-month follow-up period, three patients were cured of hypertension and four showed improvement. Only one patient failed to respond: Failure was caused by an occluded left renal artery 3 months after the procedure. Renal angiographic studies were repeated in six patients after 6 months of follow-up and showed patent vessels in five and reoccurrence of a slight renal-artery stenosis in one. In one patient angiographic control studies done after 3 months showed an occluded renal artery. In five patients mean pressure gradient across the renal-artery stenoses was 89 ± 22.8 mm Hg before percutaneous transluminal dilatation and 16.4 ± 18.5 mm Hg after being controlled for 6 months. Our results indicate that percutaneous transluminal dilatation may be valuable in the treatment of renovascular hypertension.

    Article and Author Information

    • ▸From the Department of Internal Medicine and the Clinic of Nuclear Medicine, University Hospital; Zurich, Switzerland.

    • ▸Requests for reprints should be addressed to U. Kuhlmann, M.D.; Department of Internal Medicine, University Hospital, Rämistr. 100; CH 8091 Zurich, Switzerland.

      • Received May 31, 1979.
      • Accepted October 11, 1979.
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