Toxoplasma Uveitis Without Retinochoroiditis?

Excerpt

To the editor: We have read with interest the recent correspondence (1) reporting a presumptive anterior uveitis without apparent retinochoroiditis in acquired toxoplasmosis.

Although there is now little doubt that the acquired disease can result in a retinochoroiditis (2-4), an isolated anterior uveitis caused by toxoplasmosis remains speculative. The anterior chamber reaction that commonly accompanies the retinochoroiditis observed in both congenital and acquired toxoplasmosis is thought to represent a "spillover" phenomenon, that is, a hypersensitivity reaction in the anterior uvea (iris and ciliary body) to an antigenic insult in the posterior segment (5). This reaction has been experimentally produced in