Prolactin-Secreting Tumors in Men: Surgical Cure

  1. A. PONT, M.D.;
  2. RONALD SHELTON, M.D.;
  3. W. D. ODELL, M.D., Ph.D.; and
  4. CHARLES B. WILSON, M.D.
  1. San Jose, Los Angeles, and San Francisco, California

    Abstract

    Two men presented with decreasing libido and impotence. Endocrine evaluation showed that they both had low levels of serum testosterone and a prolactin-secreting adenoma. Transsphenoidal removal of their tumors resulted in normalization of serum prolactin and testosterone concentrations and normalization of sexual function. These patients represent the first two nonacromegalic men with prolactin-secreting tumors and hypogonadism in whom surgical resection of their tumors resulted in a complete clinical and biochemical remission. We discuss the effects of elevated prolactin on male sexual function.

    Article and Author Information

    • ▸From the Division of Endocrinology, Santa Clara Valley Medical Center, San Jose, the Division of Endocrinology, Department of Medicine, UCLA Medical Center, Los Angeles, and the Department of Neurosurgery, University of California Medical Center, San Francisco; California.

    • ▸Requests for reprints should be addressed to Allan Pont, M.D.; Santa Clara Valley Medical Center, 751 South Bascom Avenue; San Jose, CA 95128.

      • Received February 2, 1979.
      • Accepted May 4, 1979.
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    1. Ann Intern Med August 1, 1979 vol. 91 no. 2 211-213
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