Bromocriptine and Pituitary Disorders

  1. J. KELLETT, M.D.; and
  2. H. G. FRIESEN, M.D.
  1. Department of Physiology, University of Manitoba;
    Winnipeg, Manitoba
    , Canada

    Excerpt

    There have been four important medical advances that in a short time have combined to focus attention on the pituitary gland and disorders affecting it. These include a better appreciation of the neuroendocrine mechanisms that regulate pituitary hormone secretion, the recognition that hyperprolactinemia is implicated in approximately 25% of cases of secondary amenorrhea, improved radiologic techniques that allow the detection of pituitary microadenomas that previously went unrecognized, and restoration of normal endocrine function in a high percentage of patients after complete removal of these tumors using the transsphenoidal route. The early identification of these tumors is therefore important.

    The introduction

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