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Hepatitis-Associated Lipid Storage Myopathy
- BERNARD M. PATTEN, M.D., F.A.C.P.;
- J. MARC SHABOT, M.D.;
- JACK ALPERIN, M.D.; and
- RONALD F. DODSON, Ph.D.
Abstract
We report the case of a 23-year-old woman who developed severe myalgias in association with mild hepatitis B surface antigen-positive hepatitis. Muscle biopsy showed myriads of microvacuoles filled with neutral lipid. Prednisone therapy was associated with complete clearing of all clinical and laboratory abnormalities. Since muscle carnitine levels were normal before treatment, we conclude that infection with hepatitis virus may induce non-carnitine-deficient lipid storage myopathy in man.
Article and Author Information
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▸From the Department of Neurology, Baylor College of Medicine, Houston; and the Department of Medicine, University of Texas Medical Branch at Galveston, Galveston, Texas.
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Grant support: by a grant from the Muscular Dystrophy Associations of America, and a gift from Rosalie and Joe Eisenberg, San Antonio, Texas.
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▸Requests for reprints should be addressed to Bernard M. Patten, M.D.; Department of Neurology, Baylor College of Medicine; Houston, TX 77030.
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- Received March 7, 1977.
- Accepted June 27, 1977.
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