Acute Severe Aortic Regurgitation
Pathophysiology, Clinical Recognition, and Management
- JOEL MORGANROTH, M.D.;
- JOSEPH K. PERLOFF, M.D.;
- STEVEN M. ZELDIS, M.D.; and
- W. BRUCE DUNKMAN, M.D.
Abstract
Acute severe aortic regurgitation is a relatively unfamiliar, though life-threatening, disease. We review its diverse causes, anatomic faults, and hemodynamic sequelae and set the stage for an understanding of the clinical manifestations in light of their physiologic mechanisms. Clinical information includes the natural history, physical signs (physical appearance, systemic arterial pulse, jugular venous pulse, precordial palpation, auscultation), electrocardiogram, and chest roentgenogram. Echocardiographic features are especially emphasized and the need for prompt diagnosis and surgical intervention underscored, even in the setting of active infective endocarditis.
Article and Author Information
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▸From the Hospital of the University of Pennsylvania and the Veterans Administration Hospital of Philadelphia, and the Cardiovascular Section, Department of Medicine, University of Pennsylvania School of Medicine; Philadelphia, Pennsylvania.
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▸Requests for reprints should be addressed to Joel Morganroth, M.D.; Cardiovascular Section, Hospital of the University of Pennsylvania, 3400 Spruce St.; Philadelphia, PA 19104.
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