Chronic Hepatitis in Hemophilia
- LEONARD B. SEEFF, M.D.; and
- JAY HOOFNAGLE, M.D.
- Departments of Medicine, Veterans Administration Hospital and Georgetown University School of Medicine; Washington, D.C.
Excerpt
Persons with hemophilia are at unusually high risk of developing acute viral hepatitis as a result of their need for repeated treatment with blood products. Although less than one fourth of adult hemophiliac patients have a history of acute hepatitis, at least three fourths of them can be shown by serologic tests for the hepatitis B surface antigen (HBsAg) and antibody (antiHBs) to have been exposed to type B hepatitis (1). Some recent evidence has suggested that chronic hepatitis might also be common in this population (2), a consequence of treatment with blood products that might have been predicted. Prospective
This 100-word excerpt has been provided in the absence of an abstract.
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