Absence of Lymphocyte Immunoglobulin Production in Chronic Lymphocytic Leukemia and Multiple Myeloma

  1. JAMES P. CROWLEY, M.D.;
  2. W. HALOWELL CHURCHILL, M.D.;
  3. JAMES SIMON, PH. D.; and
  4. MAURICE M. ALBALA, M.D., F.A.C.P.
  1. Drs. Crowley, Simon, and Albala
    Division of Clinical Hematology
    Rhode Island Hospital and Brown University
    Providence, Rl 02902

    Dr. Churchill
    Department of Medicine
    Harvard Medical School
    Boston, MA 02115

    Excerpt

    The combination of chronic lymphocytic leukemia and multiple myeloma is a rare and noteworthy combination of diseases (1). We recently treated a patient with both these diseases. Since recent studies (2, 3) have emphasized the depressive effect of multiple myeloma on normal lymphocyte immunoglobulin production, we thought it sufficiently of interest to report the results of our study of the immunoglobulin production of her abnormal peripheral blood lymphocytes.

    The patient was an 80-year-old widow hospitalized initially because of back pain secondary to a compression fracture of T10. Her past history included a resection of a localized carcinoma of the cervix

    This 100-word excerpt has been provided in the absence of an abstract.

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