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Viremia with Herpes Simplex Type 1 in Adults
Four Nonfatal Cases, One with Features of Chicken Pox
- SIRUS NARAQI, M.D.;
- GEORGE GEE JACKSON, M.D., F.A.C.P.; and
- OLGA M. JONASSON, M.D., F.A.C.S.
Abstract
Recovery of herpes simplex virus (HSV) Type 1 from the blood buffy coat of four adults is reported for the first time. All of the patients had vesicular stomatitis and facial vesicles; two also had either keratoconjunctivitis or disseminated skin lesions. The infection was not the primary one with HSV in any of them. Two of three patients who had renal failure were receiving immunosuppressive drugs; one patient was normal except for alcoholism and diabetes. None developed signs of visceral organ infection and all recovered within 2 to 4 weeks. The findings demonstrate the occurrence of heretofore unrecognized nonfatal HSV Type 1 viremia in both healthy and immunosuppressed adults. The viremia, presumably owing to infected leukocytes, can occur regardless of the presence of serum antibody, and may or may not be associated with the disseminated lesions.
Article and Author Information
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▸ From the Section of Infectious Diseases, Department of Medicine, and the Division of Transplant, Department of Surgery, University of Illinois Hospital, Abraham Lincoln School of Medicine, University of Illinois; and the West Side Veterans Administration Hospital; Chicago, Illinois.
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▸Reprint requests should be addressed to George Gee Jackson, M.D.; Section of Infectious Diseases, Department of Medicine, University of Illinois, P.O. Box 6998; Chicago, IL 60680.
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- Received February 23, 1976.
- Accepted April 22, 1976.
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