A Scleroderma-like Syndrome with Fasciitis, Myositis, and Eosinophilia

Excerpt

Recent reports (1, 2) have identified patients who had eosinophilia, hypergammaglobulinemia, and pain and swelling of the extremities with diffuse thickening and inflammation of the fascia or subcutaneous tissues, or both. Shulman's patients (1) had onset after unusual physical exertion. The syndrome resembled scleroderma (3) or mixed connective tissue disease (4), but no patients had Raynaud's phenomenon, impaired esophageal motility, other visceral sclerosis, antinuclear factor, or extractable nuclear antigen (2). This report describes a patient with similar features who also had mild myositis and has achieved remission.

A 28-year-old white male engineer noted stiffness, swelling, and painful cramps in his