IgA Myeloma Globulin and Bence Jones Proteinuria in Diffuse Plasmacytoma of Small Intestine

Excerpt

Whether single or multiple, primary plasmacytomas of the small intestine are usually nodular and circumscribed tumors (1, 2), whereas alpha chain disease is usually characterized by a diffuse plasma cell proliferation of the whole length of the small intestine and of mesenteric lymph nodes (3, 4). This disease affects young patients of particular geographic origin and may include most cases of so-called "Mediterranean-type" of abdominal lymphoma with malabsorption (5). We have studied a Turkish patient with clinicopathologic features analogous to those of alpha chain disease. We found in him a true IgA myeloma globulin and Bence Jones protein.

A 40-year-old