Risks of Repeated Immunization

  1. L. FRED AYVAZIAN, M.D.
  1. Pulmonary Disease Section
    Veterans Administration Hospital
    East Orange, New Jersey 07019

    Excerpt

    To the editor: In their paper "Repeated Immunization: Possible Adverse Effects," White, Adler, and McGann (1) report on less than 10% of 700 male employees at Fort Derrick who since 1956 had received multiple immunizations; despite some interesting minor laboratory abnormalities in this group, the authors conclude that chronic stimulation of the immunoglobulin-stimulating system in the human seems to cause no adverse effects, unlike amyloid disease, myeloma, and hypersensitivity reported in laboratory animals. As in a similar study referred to, that is, the soldiers receiving influenza vaccine, the subjects studied were always or almost always men well above adolescent age.

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