Cessation of Paroxysmal Supraventricular Tachycardias by Parasympathomimetic Interventions

  1. HERMAN O. KLEIN, M.D., F.A.C.P.; and
  2. BRIAN F. HOFFMAN, M.D.
  1. Bronx and New York, New York

    Abstract

    The mode of cessation of 39 episodes of supraventricular tachycardias during reflex vagal stimulation was studied in 11 patients. In each instance slowing of supraventricular tachycardia was observed before its cessation. The findings are consonant with present concepts of the electrophysiologic behavior of ectopic automatic cells and reentrant pathways of conduction and their response to acetylcholine. Descriptions of the behavior of supraventricular tachycardias should be more accurate.

    Article and Author Information

    • ▸From the Division of Cardiology, Department of Internal Medicine, the Albert Einstein College of Medicine, Bronx, New York; and the Department of Pharmacology, College of Physicians and Surgeons of Columbia University, New York, New York.

    • Grant support: Program Project Grant (1-POL-HE12738), National Institutes of Health.

    • ▸Requests for reprints should be addressed to Herman O. Klein, M.D., Cardiology Service, Meir General Hospital, Kfar-Saba, Israel.

      • Received September 17, 1973.
      • Accepted March 21, 1974.
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