Significance of Alcohol-Induced Hypertriglyceridemia in Patients with Type IV Hyperlipoproteinemia

  1. JACK H. MENDELSON, M.D.; and
  2. NANCY K. MELLO, PH.D.
  1. Department of Psychiatry, Harvard Medical School, Alcohol and Drug Abuse Research Center, McLean Hospital,
    Boston, Massachusetts
  2. Laboratory of Alcohol Research, National Institute of Alcohol Abuse and Alcoholism, National Institute of Mental Health,
    Rockville, Maryland

    Excerpt

    The relation: between alcohol abuse and cardiac, pancreatic, and hepatic disease are still an enduring enigma in biomedical science. Two recent findings suggest that alcohol induces elevations in triglyceride levels that may in turn contribute to cardiac and gastrointestinal disorders in those individuals with a type IV hyperlipidemia (1, 2). The heuristic value of these findings is obvious in view of the high mortality associated with cardiac disease and the numerous medical complications of chronic alcohol abuse.

    Ginsberg and associates (2) report, on pages 143-149 of this issue, that even relatively small amounts of alcohol may increase plasma triglyceride levels

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    1. Ann Intern Med February 1, 1974 vol. 80 no. 2 270-271
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