Gaucher's Disease and Coagulation Factors

Excerpt

To the editor: The concurrence of two unusual disorders in one patient has led us to investigate the relationship between them.

Patient H.G. is a 52-year-old man with Gaucher's disease; the diagnosis made 35 years earlier in him and two of four siblings. He has had thrombocytopenia for many years. He was seen here by us because of a tender right lower-quadrant mass of 6 weeks' duration. He had a Grade III/IV holosystolic apical cardiac murmur, massive hepatosplenomegaly, and a firm mass in the right side of the abdomen, from the inguinal ligament to the liver and, laterally, to the