Digital Capillary Blood Flow in Clubbing
85Kr Studies in Hereditary and Acquired Cases
- STEFAN N. RACOCEANU, M.D.;
- MILTON MENDLOWITZ, M.D.;
- ABYSSINIA F. SUCK, M.D.;
- ROBERT L. WOLF, M.D.; and
- NOSRAT E. NAFTCHI, Ph.D.
Abstract
The disappearance rate of krypton-85 (85Kr) was measured after it was injected into the fingertip pulp in 10 normal subjects and in 8 patients with acquired clubbing and 5 with hereditary clubbing. Each subject's digital vessels were brought to a stable dilation before the injection, by indirect heating for 1 hour. The disappearance rate was unequivocally more rapid in the patients with acquired clubbing and normal in the patients with hereditary clubbing. This may indicate that capillary blood flow is increased in acquired clubbing, and, since the increased capillary flow is nutritional, this factor may, at least in part, be responsible for the tissue hypertrophy and hyperplasia in acquired clubbing. The factors causing the more stable hereditary clubbing remain unknown.
Article and Author Information
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▸From the Department of Medicine, The Mount Sinai School of Medicine of the City University of New York, New York, N.Y.
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▸Requests for reprints should be addressed to Milton Mendlowitz, M.D., The Mount Sinai School of Medicine, Fifth Ave. and 100th St., New York, N.Y., 10029
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- Received June 7, 1971.
- Accepted August 18, 1971.
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