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Hepatitis-Associated Antigen and Hepatocellular Carcinoma in Taiwan
- MYRON J. TONG, M.D., Ph.D.;
- SHIH-CHIEN SUN, M.D.;
- BERTON T. SCHAEFFER, M.D.;
- NAI-KWEI CHANG, M.D.;
- KWANG-JUEI LO, M.D.; and
- ROBERT L. PETERS, M.D.
Abstract
Serums from 55 patients with primary hepatocellular carcinoma were examined for the presence of hepatitis-associated antigen (HAA). Forty-four (80%) had the antigen in their serums; alpha fetoglobulins were detected in 32 of 55 serums analyzed (58%). One hundred and thirty-eight of 943 (14.6%) healthy Chinese control subjects with normal serum glutamic-pyruvic transaminase activity had HAA in their serums. There was no apparent correlation between the presence of alpha fetoglobulins and HAA positivity in patients with hepatocellular carcinoma.
Article and Author Information
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▸From the Departments of Clinical Investigation and Pathology, U.S. Naval Medical Research Unit No. 2; and the Departments of Gastroenterology and Medical Research, Chinese Veterans General Hospital; Taipei, Taiwan; and the Department of Pathology, University of Southern California School of Medicine, John Wesley Hospital, Los Angeles, Calif.
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Opinions and assertions contained herein are those of the authors and are not to be construed as official or reflecting the views of the Navy Department or the Naval Service at large.
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Supported by funds for Work Unit MR005.09.01-0114A from the Bureau of Medicine and Surgery, U. S. Navy, Bethesda, Md.
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▸Requests for reprints should be addressed to Myron J. Tong, M.D., Los Angeles County-USC Medical Center, Box 784, 1200 N. State St., Los Angeles, Calif. 90033
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- Received May 24, 1971.
- Accepted July 21, 1971.
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