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Resolution of Chronic Eosinophilic Pneumonia with Corticoid Therapy
Demonstration by Needle Biopsy
Abstract
A case of needle biopsy-documented resolution of chronic eosinophilic pneumonia after corticoid therapy is described. The patient presented with nonspecific clinical symptoms, but persistent peripheral blood eosinophilia, migratory pulmonary infiltrates, and pulmonary function impairment suggested the diagnosis; histological proof was secured by means of percutaneous needle biopsy. The patient was then given corticosteroids. Several clinical, radiological, and functional remissions and exacerbations closely followed variations in steroid dosage. A second needle biopsy, done during a period of remission, confirmed the previous assumption by others that steroid therapy leads to resolution rather than organization of the alveolar and interstitial processes of chronic eosinophilic pneumonia.
Article and Author Information
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▸From the Departments of Medicine and Pathology and the Unit for Research in Aging, the Albert Einstein College of Medicine; and the Chest Service, the Bronx Municipal Hospital Center; Bronx, N.Y.
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Supported in part by grant HE 12766, U.S. Public Health Service, Washington, D.C.; and contract U-2041, New York City Health Research Council, New York, N.Y.
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▸Requests for reprints should be addressed to Harvey Wolinsky, M.D., Albert Einstein College of Medicine, Department of Medicine, 1300 Morris Park Ave., Bronx, N.Y. 10461
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- Received December 21, 1970.
- Accepted February 23, 1971.
