RSS Feeds
Q Fever Hepatitis
- H. L. DUPONT, M.D.;
- R. B. HORNICK, M.D., F.A.C.P.;
- H. S. LEVIN, M.D.;
- M. I. RAPOPORT, M.D.; and
- T. E. WOODWARD, M.D., F.A.C.P.
Abstract
Hepatic involvement was appraised in three individuals with Q fever. One patient presented with moderately severe hepatitis without pulmonary involvement, whereas the other two were volunteers participating in a trial to evaluate Q fever vaccine. Findings suggest that liver involvement is common in Q fever and that histologic changes are more striking than blood chemical findings. The case of naturally acquired disease shows the clinical variability of Q fever, as extensive granulomatous hepatic infiltration occurred without detectable pulmonary involvement. Q fever is becoming more prevalent throughout the United States and should be considered in patients whose illness resembles "atypical pneumonia" or "infectious hepatitis."
Article and Author Information
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▸From the University of Maryland School of Medicine, Baltimore, Md.
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Supported in part by U. S. Army contract DA-17-67-C-7057; and by contract RR-33, U. S. Public Health Service; Washington, D.C.
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▸Requests for reprints should be addressed to Herbert L. DuPont, M.D., Division of Infectious Diseases, University of Maryland, Baltimore, Md. 21201
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- Received August 4, 1970.
- Accepted November 2, 1970.
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