Cardiac Disease and Its Treatment—Some Physiological Correlations

  1. GLENN A. LANGER, M.D.;
  2. ALLAN J. BRADY, Ph.D.;
  3. KENNETH I. SHINE, M.D.; and
  4. JOY A. SOPIS, Ph.D.
  1. Los Angeles, California

    Abstract

    Certain aspects of cardiac function as related to the normal and diseased heart are summarized. Topics discussed include: [1] myocardial ultrastructuralfunctional relationships; [2] the process of electrical excitation and conduction and the basic physiology of arrhythmias and conduction defects; [3] methods of evaluation of myocardial failure in the patient and present concepts of the cellular basis of heart failure; and [4] the role of the ions in the control of the myocardial contractile process and the possible relationships between ionic flux and digitalis action.

    Article and Author Information

    • ▸An edited transcription of the Clinical Case Conference arranged by the Departments of Medicine and Physiology of the UCLA School of Medicine, Los Angeles, Calif.

    • ▸Requests for reprints should be addressed to G.A. Langer, M.D., Department of Medicine, UCLA School of Medicine, Los Angeles, Calif. 90024

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