Vitiligo in Graves' Disease

  1. YUKIO OCHI, M.D.; and
  2. LESLIE J. DEGROOT, M.D.
  1. Chicago, Illinois
  1. Requests for reprints should be addressed to Leslie J. DeGroot, M.D.,
    950 E. 59th St., Chicago, Ill. 60637

SUMMARY

Six instances of vitiligo involving chiefly the hands and feet occurred among 90 patients with Graves' disease. The vitiligo usually preceded the onset of the symptoms of Graves' disease. Autoantibodies against thyroid were present in five of six patients, and long-acting thyroid stimulator (LATS) was present in three of six. The vitiligo may be another manifestation of autoimmunity. When present it is a helpful clinical diagnostic point suggesting the presence of Graves' disease.

Article and Author Information

  • From the Thyroid Study Unit, Department of Medicine, University of Chicago, Chicago, Ill.

  • Supported in part by grant AM-13377, U. S. Public Health Service, Washington, D. C.; and by grant P-298, the American Cancer Society, New York, N. Y.

    • Received April 7, 1969.
    • Accepted June 27, 1969.
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