RSS Feeds
The Circulating Lymphocyte—Its Role in Infectious Mononucleosis
- LAWRENCE N. CHESSIN, M.D.;
- PHILIP R. GLADE, M.D.;
- JULIUS A. KASEL, PH.D.;
- HAROLD L. MOSES, M.D.;
- RONALD B. HERBERMAN, M.D.; and
- YASHAR HIRSHAUT, M.D.
- Requests for reprints should be addressed to Sheldon M. Wolff, M.D., Clinical Director, National Institute of Allergy and Infectious Diseases, Bldg. 10, Room 11-N-232, National Institutes of Health, Bethesda, Md. 20014.
SUMMARY
This Combined Clinical Staff Conference presents some of the newer findings in basic biology of the lymphocyte and illustrates how investigational techniques of tissue culture, virology, immunology, and fine structural analysis have been useful in studying some salient clinical features in infectious mononucleosis. Recent clinical studies and findings are summarized.
The proliferative potential of the circulating lymphocyte and the isolation and characterization of continuous lymphoid cell lines derived from peripheral blood of patients with infectious mononucleosis are discussed. The microbial isolation pattern from patients and specific host immunologic responses are presented in light of recently identified virus-like particles in cell lines derived from patients with infectious mononucleosis.
Article and Author Information
-
This is an edited transcription of a Combined Clinical Staff Conference at the Clinical Center, Bethesda, Md., by the National Institute of Allergy and Infectious Diseases, National Institutes of Health, U. S. Department of Health, Education, and Welfare.
-
- Received May 22, 1968.
- Accepted May 29, 1968.
