Accelerated Nephrosclerosis and Postpartum Acute Renal Failure in Normotensive Patients

  1. RICHARD D. WAGONER, M.D.;
  2. KEITH E. HOLLEY, M.D.; and
  3. WILLIAM J. JOHNSON, M.D., F.A.C.P.
  1. Requests for reprints should be addressed to Richard D. Wagoner, M.D., Mayo Clinic,
    Rochester, Minn. 55901
    .

SUMMARY

The cases of three patients in whom acute renal failure developed insidiously during the postpartum period are reported. Each patient was normotensive and historically exhibited no prior evidence of renal disease. The histologic findings most closely resembled those of accelerated nephrosclerosis or of progressive systemic sclerosis. These cases emphasize the need for earlier recognition and encourage further investigation of this poorly understood syndrome.

Article and Author Information

  • From the Section of Medicine and the Section of Experimental and Anatomic Pathology, Mayo Clinic and Mayo Foundation, Rochester, Minn.

    • Received January 15, 1968.
    • Accepted April 11, 1968.
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