Ischemic Heart Disease in Young Adults

Metabolic and Angiographic Diagnosis and the Prevalence of Type IV Hyperlipoproteinemia

  1. DAVID H. BLANKENHORN, M.D., F.A.C.P.;
  2. H. P. CHIN, PH.D.; and
  3. FRANCIS Y. K. LAU, M.D., F.A.C.P.
  1. Requests for reprints should be addressed to David H. Blankenhorn, M.D.,
    2025 Zonal Ave., Los Angeles, Calif. 90033
    .

SUMMARY

A study of 15 young patients with known or suspected coronary atherosclerosis by a combined metabolic-angiographic protocol is reported. Among 10 patients with coronary disease proved by angiography, 5 had type IV hyperlipoproteinemia. Early changes in triglyceride levels and pre-beta lipoprotein, which occur 2 to 7 days after start of 85% carbohydrate diet, appear useful in the diagnosis of type IV hyperlipoproteinemia.

Article and Author Information

  • From the University of Southern California School of Medicine, Los Angeles, Calif.

  • Supported in part by grants HE 07197 and FR 00043, U. S. Public Health Service, Washington, D. C.

    • Received January 22, 1968.
    • Accepted March 25, 1968.
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