Nonpsychic Effects of Lysergic Acid Diethylamide

  1. KURT HIRSCHHORN, M.D.; and
  2. MAIMON M. COHEN, PH.D.
  1. Department of Pediatrics
    Division of Medical Genetics
    The Mt. Sinai School of Medicine
    New York, N. Y.
  2. Division of Human Genetics
    Department of Pediatrics
    State University of New York at Buffalo School of Medicine and the Buffalo Children's Hospital
    Buffalo, N. Y.

    Excerpt

    The acute and the chronic psychotomimetic potentials of the hallucinogen lysergic acid diethylamide (LSD) have been documented (1). That additional effects of LSD should come under scrutiny at this time is particularly pertinent considering the supposed widespread use of this drug among the population. Recent investigations have demonstrated that small doses of LSD (as low as 0.001 µg/ml) yielded a two- to threefold increase of chromosomal damage in comparison with untreated control cells. A similar in vivo effect was predicted by the finding of increased chromosomal abnormalities in one patient receiving LSD therapy for a psychiatric disorder (2). This observation

    This 100-word excerpt has been provided in the absence of an abstract.

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