Controlled Ventilation with Intermittent Positive-Pressure Breathing in the Management of Acute Ventilatory Failure Associated with Chronic Obstructive Pulmonary Disease

  1. EARLE B. WEISS, M.D.; and
  2. MAURICIO J. DULFANO, M.D.
  1. Requests for reprints should be addressed to Earle B. Weiss, M.D., Lung Station (Tufts), Boston City Hospital,
    818 Harrison Ave., Boston, Mass. 02118
    .

Excerpt

Controlled mechanical ventilation may be employed for ventilatory support in patients with respiratory failure when assisted ventilation fails. The purpose of controlled ventilation is to reduce patient respiratory control and effort and to substitute adequate artificial ventilation, thereby providing time for appropriate medical therapy. With improvement the patient's own ventilatory effort may be capable of maintaining normal or clinically stable balance. These principles have been adequately demonstrated in acute ventilatory failure with volume-cycled respirators (1, 2). It was the purpose of this prospective study to evaluate in patients with chronic obstructive lung disease, a group usually difficult to manage during

Article and Author Information

  • From the Department of Medicine, Tufts University School of Medicine, and the Lung Station (Tufts) and 1 and 3 Medical Services (Tufts), Boston City Hospital, Boston, Mass.

  • This study was supported in part by grants from the Pittsfield Anti-Tuberculosis Association, Pittsfield, Mass., and from The Council for Tobacco Research, New York, N. Y.

  • Dr. Weiss was supported in this study by postdoctoral fellowship 5-F2-HE-23, 300, National Heart Institute, National Institutes of Health, Bethesda, Md.

    • Received April 10, 1967.
    • Accepted May 29, 1967.
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