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Iatrogenic Factors in Infectious Disease
- HARRY N. BEATY, M.D.; and
- ROBERT G. PETERSDORF, M.D., F.A.C.P.
- Requests for reprints should be addressed to Harry N. Beaty, M.D., Department of Medicine, King County Hospital, 325 9th Ave., Seattle, Wash. 98104.
Excerpt
The term "iatrogenic" is used commonly to designate diseases caused by the ministrations of a physician. A review of this subject produces an overwhelming number of references which are readily available in the current medical literature in the form of symposia, review articles, monographs, and case reports. In addition, there is a constant barrage of warning letters from pharmaceutical companies and the Food and Drug Administration. Despite this preoccupation with iatrogenic disease, most physicians appear to feel secure in the belief, that "iatrogenic disease" is a consequence of carelessness or ineptitude on the part of some other physician. The generalization
Summario in Interlingua
Morbos iatrogenic es non necessarimente un effecto de negligentia o de incuria, sed illos etiam pote resultar de juste e correcte mesuras therapeutic o diagnostic. A base de illustrative reportos de casos, certes del causas commun de morbo iatrogenic observate in le patientes de un servicio de morbo infectiose es commentate. Istos include manifestationes toxic e allergic de therapia antimicrobial, le problema de superinfectiones, e le hasardos de seligite mesuras diagnostic e therapeutic.
Es estimate que in inter 50 e 90 pro cento del occasiones le administration de antibioticos es interprendite sin nette indicationes. Cinquanta-un pro cento del complicationes iatrogenic resulta del administration de pharmacos e primarimente de pharmacos antimicrobial. Plures del major manifestationes de reactiones allergic e toxic es commentate.
Superinfectiones pote occurrer in chronicamente malade e invalidate patientes in qui le mechanismos de resistentia es alterate (1) per le morbo subjacente o (2) per le administration del pharmacos usate. Tamen, tal infectiones etiam pote occurrer in relativemente robuste patientes in le curso de un therapia antimicrobial.
Le numero del disponibile mesuras diagnostic e therapeutic accresce progressivemente. Mesmo relativemente simple manovras pote esser associate con complicationes major, e le crescentemente complexe mesuras usate in seriemente malade patientes multiplica le riscos de complication iatrogenic.
Article and Author Information
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From the Department of Medicine, University of Washington School of Medicine at King County Hospital, Seattle, Wash.
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- Received June 9, 1966.
- Accepted June 14, 1966.
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