Severe Mechanical Hemolytic Anemia Due to Valvular Heart Disease Without Prosthesis

  1. SAUL ZIPEROVICH, M.D.; and
  2. H. W. PALEY, M.D.
  1. Requests for reprints should be addressed to H. W. Paley, M.D., Director, Cardiopulmonary Laboratories, Mount Zion Hospital and Medical Center,
    1600 Divisadero St., San Francisco, Calif. 94115
    .

Excerpt

Anemia, after the replacement of a damaged heart valve, was first reported in 1954 when Rose and associates (1) described it after the insertion of a prosthetic valve of the Hufnagel type in the descending aorta for correction of aortic insufficiency. Hemolysis after open heart surgery was reported in dogs by Stohlman, Sarnoff, Case, and Ness (2) after the insertion of a prosthetic valve (Hufnagel type) encased in a lucite tube into the thoracic aorta. Later, Sayed and associates (3) observed the phenomenon in one patient after insertion of a Teflon patch for correction of atrial septal defect. Although subsequently

This 100-word excerpt has been provided in the absence of an abstract.

Acknowledgment

The authors wish to express their appreciation to Lawrence D. Petz, M.D., for his helpful suggestions.

Summario in Interlingua

Es presentate le caso de un patiente in qui valvuloplastia mitral, tentate—insuccessosemente—como tractamento de insufficientia mitral resultava in un marcatemente plus sever regurgitation mitral sequite de anemia hemolytic. Subsequentemente le patiente, un femina, disveloppava congestive insufficientia cardiac, e un reimplaciamento del valvula mitral per un prosthese de Starr-Edwards esseva effectuate. Post iste operation, le hemolyse cessava quasi completemente. Es concludite que le hemolyse habeva resultate ab factores mechanic associate con un marcate turbulentia del sanguine fluente a transverso le incompetente valvula mitral. Il pare que isto es le prime publicate reporto de un verificate caso de sever mechanic anemia hemolytic in un patiente con morbo valvular sin le presentia de materiales prosthetic.

Article and Author Information

  • From the Cardiopulmonary Laboratories and the Department of Medicine, Mount Zion Hospital and Medical Center, San Francisco, Calif.

    • Received April 1, 1966.
    • Accepted May 19, 1966.
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