RSS Feeds
Rheumatic Fever in Children and Adolescents
A Long-term Epidemiologic Study of Subsequent Prophylaxis, Streptococcal Infections, and Clinical Sequelae
VII. Cardiac Changes and Sequelae
- ALVAN R. FEINSTEIN, M.D.;
- HARRISON F. WOOD, M.D.;
- MARIO SPAGNUOLO, M.D.;
- ANGELO TARANTA, M.D.;
- SARAN JONAS, M.D.;
- EDITH KLEINBERG, B.S.; and
- ESTHER TURSKY, R.N.
- Requests for reprints should be addressed to Alvan R. Feinstein, M.D., Department of Internal Medicine, Yale University School of Medicine, 333 Cedar Street, New Haven 11, Connecticut.
Excerpt
What are the cardiac sequelae of acute rheumatic fever? How often does insidious valvular scarring bring rheumatic cardiac damage to patients who initially seemed free of it? How well can we identify the patients who will do poorly or those who will remain permanently free of rheumatic heart disease? Is death at a young age invariably due to persistent or recurrent "rheumatic activity"?
Although these and other clinical questions about rheumatic fever have often been asked and answered in the past, the existing answers have come from studies whose methods could not provide entirely satisfactory explorations of the issues involved.
Article and Author Information
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From Irvington House, Irvington-on-Hudson, New York, and the Departments of Medicine and Pediatrics, New York University School of Medicine, New York.
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This work was supported in part by the National Heart Institute grant H-1595 (C-1-8), American Heart Association, New York Heart Association, Westchester Heart Association, and Wyeth Laboratories.
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Drs. Feinstein and Wood are currently with the Department of Internal Medicine and the Department of Pediatrics, respectively, Yale University School of Medicine, New Haven, Connecticut.
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- Received January 30, 1963.
- Accepted June 10, 1963.
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