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The Occurrence of Carcinoma in "Hot" Thyroid Nodules
Report of Two Cases
- FRANK O. BECKER, M.D.;
- PETER G. ECONOMOU, M.D.; and
- THEODORE B. SCHWARTZ, M.D., F.A.C.P.
- Requests for reprints should be addressed to Theodore B. Schwartz, M.D., Section of Endocrinology and Metabolism, Presbyterian-St Luke's Hospital, 1753 West Congress Parkway, Chicago, Illinois.
Excerpt
When the physician finds a patient with nodular goiter, he must consider the possibility of malignancy and decide whether surgery is indicated. Surgeons, generally, have found that the incidence of carcinoma in nodular goiter is high and recommend immediate surgery (1-5). Internists (6-8), on the other hand, conclude the incidence is low and in most instances suggest medical management.
With regard to solitary nodules, the advent of the scintogram has led to more agreement of opinion. This technique permits a qualitative distinction between hyperfunctioning ("hot") and hypofunctioning ("cold") nodules. Means (9), in 1950, stated: "So far we have never found
This 100-word excerpt has been provided in the absence of an abstract.
Summario in Interlingua
Es generalmente acceptate que nodulos thyroidee que manifesta hyperfunction in le scintogramma non es maligne. Iste regula general non es sin exception. Duo patientes es presentate con solitari nodulos thyroidee in hyperfunction que esseva recognoscite in studios histologic como afficite de carcinoma papillari intra un adenoma. Radioautogrammas monstra nulle acceptation supra le cellulas tumoric sed un augmento del acceptation in le circumjacente parenchyma. Le prime patiente habeva un nodulo thyroidee dur e symptomas suggerente hyperthyroidismo sed nulle altere constatationes physic o laboratorial in supporto de iste diagnose. Le impression clinic esseva un de malignitate. Le secunde patiente esseva asymptomatic, excepte que ille habeva un nodulo thyroidee que non esseva supprimibile con L-tri-iodothyronina, un facto que suggere que iste nodulo esseva autonome. Intervention chirurgic esseva effectuate in ambe casos a base del total evalutation clinic plus tosto que in dependentia de exclusivemente le resultatos del scintogramma. Ben que il pare probabile que le presentia de malignitates intra hyperfunctionante nodulos es rar, le constatation de un nodulo hyperfunctionante per se non exclude un diagnose de carcinoma.
Article and Author Information
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Doctor Becker is a trainee of the United States Public Health Service.
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- Received December 3, 1962.
- Accepted January 9, 1963.
