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Simplified Test for Hematuria
- THOMAS R. ELDER, M.B., CH.B.;
- JACK L. BARRY, M.D.;
- PAULINE M. FOLCIK; and
- EDWIN M. KNIGHTS, JR., M.D., F.A.C.P.
- Requests for reprints should be addressed to Edwin M. Knights, Jr., M.D., Department of Pathology, Hurley Hospital, Flint 2, Michigan.
Excerpt
Chemical tests for the detection of blood in the urine are based on the ability of hemoglobin to catalyze the oxidation of an indicator substance by hydrogen peroxide. In this investigation a new reagent stick test (Hemastix*) was evaluated. It consists of a stiff bibulous strip of cellulose in which the test end is impregnated with the reagents: o-tolidine as the indicator, cumene hydroperoxide in a stabilized form, and a citrate buffer to maintain the optimal pH. Hemoglobin catalyzes the oxidation of o-tolidine by cumene hydroperoxide to form a blue color. Also used in the investigation were commercially available tablets
This 100-word excerpt has been provided in the absence of an abstract.
Summario in Interlingua
Mille non-seligite specimens de urina ab hospitalisate patientes esseva testate pro le presentia de sanguine per medio de examines microscopic, per medio del Occultest, e per medio del nove banda a reagente Hemastix. Le autores ha constatate un nette correlation inter le tres methodos. Le plus importante discrepantia esseva que un urina con positive resultatos in le tests chimic esseva negative secundo le examine microscopic. Il es le opinion del autores que le nove test a banda con reagente es rapide, facile a executar, e un utile supplemento al microscopia in le detection de hematuria.
Article and Author Information
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From the Department of Pathology, Hurley Hospital, Flint 2, Michigan.
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↵* Registered trademark of the Ames Company, Inc., Elkhart, Indiana.
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- Received November 15, 1961.
- Accepted February 28, 1962.
