THE TREATMENT OF PNEUMONIA WITH BACITRACIN*

  1. EDWARD H. REISNER, JR., M.D.
    New York, N. Y.
    ;
  2. FREDERICK N. BAILEY, M.D.
    New York, N. Y.
    ; and
  3. EMANUEL APPELBAUM, M.D., F.A.C.P.
    New York, N. Y.

    Excerpt

    In 1945, Johnson, Anker and Meleney1 reported the discovery of an antibiotic which they called bacitracin, produced by the Tracey I strain of B. subtilis. It had a bactericidal spectrum roughly comparable to that of penicillin,2 and was well tolerated by laboratory animals3, 4 when applied locally or injected systemically. In 1947, Meleney and Johnson2 reported the first 100 cases of surgical infections treated locally with bacitracin, with results at least comparable to those obtainable with penicillin. Since then the local use of bacitracin has been successful in the treatment of infections of the skin5 and eye, and bacitracin has

    Acknowledgments

    The bacitracin used in these studies was supplied by the Ben Venue Laboratories, Pittsburgh, Pa., and the Commercial Solvents Corporation, Terre Haute, Indiana.

    Article and Author Information

    • * Received for publication March 1, 1949.

    • From the Fourth Medical Division (New York University), Bellevue Hospital, Dr. Charles H. Nammack, Director.

    • This study was supported by a grant from the United States Public Health Service.

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