Table of Contents

January 5, 2010; 152 (1)

Articles

  • Continuation of Low-Dose Aspirin Therapy in Peptic Ulcer Bleeding: A Randomized Trial

    • Joseph J.Y. Sung,
    • James Y.W. Lau,
    • Jessica Y.L. Ching,
    • Justin C.Y. Wu,
    • Yuk T. Lee,
    • Philip W.Y. Chiu,
    • Vincent K.S. Leung,
    • Vincent W.S. Wong,
    • and Francis K.L. Chan
    Ann Intern Med January 5, 2010 152:1-9; published ahead of print November 30, 2009, doi:10.1059/0003-4819-152-1-201001050-00179

    Sung and colleagues tested the idea that continuing aspirin therapy with proton-pump inhibitors after endoscopic control of peptic ulcer bleeding was not inferior to stopping aspirin therapy in adults with cardiovascular or cerebrovascular diseases. Immediately after successful endoscopic treatment, patients were randomly assigned to receive low-dose aspirin (80 mg/d) or placebo for 8 weeks. More aspirin recipients than placebo recipients had recurrent ulcer bleeding within 30 days (10% vs. 5%), but fewer aspirin recipients died (1% vs. 13%).

  • Smoking, Smoking Cessation, and Risk for Type 2 Diabetes Mellitus: A Cohort Study

    • Hsin-Chieh Yeh,
    • Bruce B. Duncan,
    • Maria Inês Schmidt,
    • Nae-Yuh Wang,
    • and Frederick L. Brancati
    Ann Intern Med January 5, 2010 152:10-17; doi:10.1059/0003-4819-152-1-201001050-00005

    To test the hypothesis that smoking cessation increases diabetes risk, possibly owing to cessation-related weight gain, Yeh and coworkers studied 10 892 middle-aged adults in the ARIC (Atherosclerosis Risk in Communities) Study. In 9 years of follow-up, patients who smoked had a higher risk for diabetes than those who never smoked. Smokers who recently quit had higher short-term risk for diabetes than former smokers and continuing smokers.

  • Association of Antiretroviral Therapy Adherence and Health Care Costs

    • Jean B. Nachega,
    • Rory Leisegang,
    • David Bishai,
    • Hoang Nguyen,
    • Michael Hislop,
    • Susan Cleary,
    • Leon Regensberg,
    • and Gary Maartens
    Ann Intern Med January 5, 2010 152:18-25; doi:10.1059/0003-4819-152-1-201001050-00006

    Antiretroviral therapy (ART) adherence predicts HIV disease progression and survival, but its effect on direct health care costs is unclear. In this cohort study based on pharmacy claims among 6833 HIV-infected adults in South Africa, high ART adherence was associated with lower mean monthly direct health care costs, particularly reduced hospitalization costs.

Academia and Clinic

  • Cultural Competency Training and Performance Reports to Improve Diabetes Care for Black Patients: A Cluster Randomized, Controlled Trial

    • Thomas D. Sequist,
    • Garrett M. Fitzmaurice,
    • Richard Marshall,
    • Shimon Shaykevich,
    • Amy Marston,
    • Dana Gelb Safran,
    • and John Z. Ayanian
    Ann Intern Med January 5, 2010 152:40-46; doi:10.1059/0003-4819-152-1-201001050-00009

    This multicenter trial evaluated the effect of cultural competency training and race-stratified performance feedback for primary care clinicians on their diabetes care. Clinicians who received training and feedback were more likely than control clinicians to acknowledge black–white disparities in diabetes care at 12 months. Among black patients of clinicians in the intervention and control groups, however, rates of achieving target hemoglobin A1c, low-density lipoprotein cholesterol, and blood pressure values did not change.

Review

  • Systematic Review: Prediction of Perioperative Cardiac Complications and Mortality by the Revised Cardiac Risk Index

    • Meredith K. Ford,
    • W. Scott Beattie,
    • and Duminda N. Wijeysundera
    Ann Intern Med January 5, 2010 152:26-35; doi:10.1059/0003-4819-152-1-201001050-00007

    This systematic review of 24 cohort studies evaluated the ability of the Revised Cardiac Risk Index (RCRI) to predict cardiac complications and death after noncardiac surgery. The RCRI discriminated moderately well between patients at low versus high risk for cardiac events after mixed noncardiac surgery, but it predicted cardiac events after vascular noncardiac surgery less well.

Perspectives

  • Perioperative Practice: Time to Throttle Back

    • Vineet Chopra,
    • Scott A. Flanders,
    • James B. Froehlich,
    • Wei C. Lau,
    • and Kim A. Eagle
    Ann Intern Med January 5, 2010 152:47-51; published ahead of print November 30, 2009, doi:10.1059/0003-4819-152-1-201001050-00184

    The United States spends more on health care than other nations, yet health outcomes remain inferior to those of many countries. Chopra and colleagues discuss how more judicious application of many perioperative practices can ensure cost-effective management and provide the greatest benefit to patients.

Clinical Guidelines

  • Recommended Adult Immunization Schedule: United States, 2010*

    • Advisory Committee on Immunization Practices
    Ann Intern Med January 5, 2010 152:36-39; doi:10.1059/0003-4819-152-1-201001050-00008

    The Advisory Committee on Immunization Practices presents the Adult Immunization Schedule for 2010. It includes recommendations for bivalent human papillomavirus vaccine and quadrivalent human papillomavirus vaccine. The schedule was approved by the American Academy of Family Physicians, American College of Obstetricians and Gynecologists, and American College of Physicians.

Editorials

  • Aspirin Withdrawal in Acute Peptic Ulcer Bleeding: Are We Harming Patients?

    • Alan N. Barkun and
    • Marc Bardou
    Ann Intern Med January 5, 2010 152:52-53; published ahead of print November 30, 2009, doi:10.1059/0003-4819-152-1-201001050-00183

    In this issue, Sung and colleagues attempt to address an important clinical quandary: In patients who develop peptic ulcer bleeding while receiving antiplatelet therapy, should antiplatelet therapy be stopped, and, if so, for how long? Their findings force us to reconsider the focus on the gut in upper gastrointestinal bleeding and remind us to consider the patient as a whole.

  • Spending More to Save More: Interventions to Promote Adherence

    • David R. Bangsberg and
    • Steven G. Deeks
    Ann Intern Med January 5, 2010 152:54-56; doi:10.1059/0003-4819-152-1-201001050-00012

    In this issue, Nachega and colleagues provide compelling data that increasing resources to enhance antiretroviral adherence among HIV-infected patients is associated with substantial cost savings even in settings where resources are scarce. The editorialists discuss these findings and suggest ways to best allocate resources that promote adherence, improve outcomes, and reduce health care costs.

  • The Revised Cardiac Risk Index Delivers What It Promised

    • Lee Goldman
    Ann Intern Med January 5, 2010 152:57-58; doi:10.1059/0003-4819-152-1-201001050-00013

    In this issue, Ford and associates summarize data from several studies that examined the ability of the RCRI to predict major cardiac complications after noncardiac surgery. The editorialist believes that these data confirm that the RCRI is the best available predictive index for this important purpose.

  • Adult Immunization Guidelines: Challenges and Opportunities

    • Robert H. Hopkins, Jr. and
    • Keyur S. Vyas
    Ann Intern Med January 5, 2010 152:59-60; doi:10.1059/0003-4819-152-1-201001050-00014

    Annually, the Advisory Committee on Immunization Practices of the Centers for Disease Control and Prevention issues a revised Adult Immunization Schedule that is approved by the major specialty societies representing physicians who care for adults, including the American College of Physicians. The changes in each year's schedule are driven by advances in our knowledge of vaccines and vaccine-preventable disease. This editorial highlights the changes to this year's schedule.

On Being a Doctor

  • Why Geriatrics?

    • Louise Aronson
    Ann Intern Med January 5, 2010 152:61; doi:10.1059/0003-4819-152-1-201001050-00015

  • Advice

    • Ellen D. Feld
    Ann Intern Med January 5, 2010 152:62; doi:10.1059/0003-4819-152-1-201001050-00016

Letters

  • Concerns About Meta-analysis of Glucose Control and Cardiovascular Disease in Type 2 Diabetes

    • John S. Yudkin and
    • Bernd Richter
    Ann Intern Med January 5, 2010 152:63; doi:10.1059/0003-4819-152-1-201001050-00017

  • Concerns About Meta-analysis of Glucose Control and Cardiovascular Disease in Type 2 Diabetes

    • Tanika N. Kelly and
    • Jiang He
    Ann Intern Med January 5, 2010 152:63-64; doi:10.1059/0003-4819-152-1-201001050-00018

  • Pulse Versus Daily Oral Cyclophosphamide in ANCA-Associated Vasculitis

    • Prasanta Padhan
    Ann Intern Med January 5, 2010 152:64; doi:10.1059/0003-4819-152-1-201001050-00019

  • Pulse Versus Daily Oral Cyclophosphamide in ANCA-Associated Vasculitis

    • Lee A. Hebert and
    • Brad H. Rovin
    Ann Intern Med January 5, 2010 152:64; doi:10.1059/0003-4819-152-1-201001050-00020

  • Pulse Versus Daily Oral Cyclophosphamide in ANCA-Associated Vasculitis

    • Stuart M. Levine
    Ann Intern Med January 5, 2010 152:65; doi:10.1059/0003-4819-152-1-201001050-00021

  • Pulse Versus Daily Oral Cyclophosphamide in ANCA-Associated Vasculitis

    • Lorraine Harper,
    • Kirsten de Groot,
    • and Caroline O. Savage
    Ann Intern Med January 5, 2010 152:65; doi:10.1059/0003-4819-152-1-201001050-00022

  • Glycemic Control in the Intensive Care Unit

    • Cesar Alaniz and
    • Robert C. Hyzy
    Ann Intern Med January 5, 2010 152:65-66; doi:10.1059/0003-4819-152-1-201001050-00023

  • Spoons Systematically Bias Dosing of Liquid Medicine

    • Brian Wansink and
    • Koert van Ittersum
    Ann Intern Med January 5, 2010 152:66-67; doi:10.1059/0003-4819-152-1-201001050-00024

  • Correction: Glucose Control and Cardiovascular Disease in Type 2 Diabetes

    Ann Intern Med January 5, 2010 152:67; doi:10.1059/0003-4819-152-1-201001050-00025

Ad Libitum

  • What I Remember Most (For S'ne, 12)

    • Sarah Leeper
    Ann Intern Med January 5, 2010 152:68; doi:10.1059/0003-4819-152-1-201001050-00026

Medical Notices

  • Medical Notices

    Ann Intern Med January 5, 2010 152:0; doi:10.1059/0003-4819-152-1-201001050-00027

Summaries for Patients

  • Benefits and Risks of Continuing Aspirin in Patients With Peptic Ulcer Bleeding

    Ann Intern Med January 5, 2010 152:I-20; published ahead of print November 30, 2009, doi:10.1059/0003-4819-152-1-201001050-00178

  • Smoking, Quitting Smoking, and the Risk for Type 2 Diabetes

    Ann Intern Med January 5, 2010 152:I-44; doi:10.1059/0003-4819-152-1-201001050-00002

  • Adherence to HIV Treatment and Costs of Care

    Ann Intern Med January 5, 2010 152:I-50; doi:10.1059/0003-4819-152-1-201001050-00003

In the Clinic

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This Issue

January 5, 2010; 152 (1)
  1. Articles
  2. Academia and Clinic
  3. Review
  4. Perspectives
  5. Clinical Guidelines
  6. Editorials
  7. On Being a Doctor
  8. Letters
  9. Ad Libitum
  10. Medical Notices
  11. Summaries for Patients
  12. In the Clinic

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