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An Electronic Practice-Based Network for Observational Comparative Effectiveness Research
- Wilson D. Pace, MD;
- Maribel Cifuentes, RN, BSN;
- Robert J. Valuck, PhD;
- Elizabeth W. Staton, MSTC;
- Elias C. Brandt, BS; and
- David R. West, PhD
- From University of Colorado Denver School of Medicine and University of Colorado Denver School of Pharmacy, Aurora, Colorado, and American Academy of Family Physicians National Research Network, Leawood, Kansas.
Abstract
The Distributed Ambulatory Research in Therapeutics Network (DARTNet) is a federated network of electronic health data from 8 organizations representing more than 500 clinicians and more than 400 000 patients. DARTNet was designed to increase knowledge of the comparative effectiveness of prescription medications and medical devices. Traditional observational comparative effectiveness research is conducted using large data sets, such as claims databases. Such databases do not provide important clinical information that is critical to understanding comparative effectiveness. By linking electronic health records, laboratory and imaging data, and administrative data from diverse and geographically disparate patients, DARTNet provides important new insight into the comparative effectiveness of oral diabetes medications, and it is ready for expansion to further enable effectiveness research.
Article and Author Information
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Grant Support: By the Agency for Healthcare Research and Quality (contract HHSA 290200500371, task order 2).
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Potential Financial Conflicts of Interest: None disclosed.
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Requests for Single Reprints: Wilson D. Pace, MD, University of Colorado Denver, School of Medicine, Department of Family Medicine, Mailstop F496, Academic Office 1, 12631 East 17th Avenue, Aurora, CO 80045-0508; e-mail, wilson.pace{at}ucdenver.edu.
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Current Author Addresses: Drs. Pace and West, Ms. Cifuentes, and Ms. Staton: University of Colorado Denver, School of Medicine, Department of Family Medicine, Mailstop F496, Academic Office 1, 12631 East 17th Avenue, Aurora, CO 80045-0508.
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Dr. Valuck: University of Colorado Denver, School of Pharmacy, Mailstop C238, Academic Office 1, 12631 East 17th Avenue, Aurora, CO 80045-0508.
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Mr. Brandt: American Academy of Family Physicians National Research Network, 11400 Tomahawk Creek Parkway, Leawood, KS 66211.
