Effect of Candesartan on Microalbuminuria and Albumin Excretion Rate in Diabetes

  1. Rudy Bilous, MD;
  2. Nish Chaturvedi, MD;
  3. Anne Katrin Sjølie, MD;
  4. John Fuller, MD;
  5. Ronald Klein, MD;
  6. Trevor Orchard, MD;
  7. Massimo Porta, MD; and
  8. Hans-Henrik Parving, MD*
  1. From Newcastle University, Newcastle upon Tyne, United Kingdom; South Tees Hospitals NHS Trust and James Cook University Hospital, Middlesbrough, United Kingdom; International Centre for Circulatory Health, National Heart and Lung Institute, Imperial College Healthcare NHS Trust, and University College London, London, United Kingdom; Odense University Hospital, Odense, Denmark; University of Wisconsin School of Medicine and Public Health, Madison, Wisconsin; University of Pittsburgh, Pittsburgh, Pennsylvania; University of Turin, Turin, Italy; and Rigshospitalet, University of Copenhagen, and Aarhus University, Copenhagen, Denmark.
    1. Figure 1.
      View larger version:
        Figure 1. Study flow diagram for patients with type 1 diabetes.

        Number of patients who did not complete renal functional assessments includes those who died or were lost to follow-up. DIRECT = Diabetic Retinopathy Candesartan Trial; MA = microalbuminuria.

      • Figure 2.
        View larger version:
          Figure 2. Study flow diagram for patients with type 2 diabetes.

          Number of patients who did not complete renal functional assessments includes those who died or were lost to follow-up. DIRECT = Diabetic Retinopathy Candesartan Trial; MA = microalbuminuria.

        • Figure 3.
          View larger version:
            Figure 3. Cumulative proportion of patients with microalbuminuria.
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          This Article

          1. Ann Intern Med July 7, 2009 vol. 151 no. 1 11-20
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