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Transient Apical Ballooning Syndrome Precipitated by Dobutamine Stress Testing
- Adam H. Skolnick, MD;
- Krista Michelin, MD;
- Ambika Nayar, MD;
- Daniel Fisher, MD; and
- Itzhak Kronzon, MD
- From New York University School of Medicine, New York, NY 10016.
Background: Transient apical ballooning syndrome, also known as takotsubo or stress cardiomyopathy, is incompletely understood. It is often precipitated by severe emotional stress; its clinical manifestations may mimic those of the acute coronary syndrome; and it is characterized by the absence of coronary artery disease and severe hypokinesis of the left ventricular apex on cardiac catheterization, both of which resolve within weeks. Because catecholamine surge may be a mechanism underlying the syndrome, dobutamine, a sympathomimetic medication commonly used in stress testing, may cause transient apical ballooning.
Objective: To report a case of transient left ventricular apical ballooning syndrome precipitated by dobutamine.
Case Report: A 53-year-old morbidly obese woman with hypertension and bronchial asthma was referred …
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