Intravenous Esomeprazole for Prevention of Recurrent Peptic Ulcer Bleeding

  1. Joseph J.Y. Sung, MD;
  2. Alan Barkun, MD;
  3. Ernst J. Kuipers, MD;
  4. Joachim Mössner, MD;
  5. Dennis M. Jensen, MD;
  6. Robert Stuart, MD;
  7. James Y. Lau, MD;
  8. Henrik Ahlbom, BSc;
  9. Jan Kilhamn, MD;
  10. Tore Lind, MD; and
  11. for the Peptic Ulcer Bleed Study Group*
  1. From the Institute of Digestive Diseases, Chinese University of Hong Kong, Hong Kong, China; McGill University Health Center, Montreal, Quebec, Canada; Erasmus MC University Medical Center, Rotterdam, the Netherlands; Medizinische Klinik und Poliklinik II, University of Leipzig, Leipzig, Germany; David Geffen School of Medicine at the University of California, Los Angeles, and Center for Ulcer Research and Education (CURE), Digestive Diseases Research Center, Los Angeles, California; Glasgow Royal Infirmary, Glasgow, United Kingdom; and AstraZeneca Research and Development, Mölndal, Sweden.
    1. Figure 1.
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        Figure 1. Study flow diagram.

        GI = gastrointestinal; ITT = intention-to-treat; PP = per-protocol.

      • Figure 2.
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          Figure 2. Kaplan–Meier estimate of the cumulative percentage of patients with recurrent bleeding within 30 days.

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